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Cellulitis (Treatment (Severe non-purulent cellulitis (Vanc + piperacillin…

- - - - penicillin, ceftriaxone, cefazoline, clindamycin
    - - IV vanc, daptomycin, or linezolid
  - - - Incision and drainage
      - Good wound care
      - Systemic abx not necessary
    - - Outpatient
        
        TMP SMX
        
        Doxycycline
        
        Linezolid
        
        incision and drainage
      - If MRSA suspected:
        
        SMX/TMP
        
        doxycycline
        
        Minocycline
    - - Collect specimens for culture and susceptibility
      - Hospitalize for empiric and parenteral with activity against MRSA
      - Vancomycin
      - Daptomycin
      - Linezolid, tedizolid
      - Telavancin
- - - - Involves deeper skin structures (surgical intervention may be necessary)