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TESTICLE SHRINKAGE (CIRCULATORY SYSTEM (HORMONAL SYSTEM (decreased sperm…
TESTICLE SHRINKAGE
22-yr old male bodybuilder, engaged to be married. He has been injecting himself with a potent, synthetic, anabolic steroid for increase in muscle mass.
Anabolic steroid use stops production of other hormones in the body including LH which produces testosterone, the abuse of steroids could be due to lack of self-confidence, performance, and endurance and to shorten recovery time between workouts.
The presence of a significant level of hormone (anabolic steroid hormone) circulating in the bloodstream can cause its target cells to decrease their number of receptors for the hormone, cells become less reactive to excessive hormone levels. (Down regulation)
HORMONES
Paracrine: the hormone acts locally by diffusing from its source to target cells in the neighborhood.
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The homeostasis level is interrupted when the hypothalamus (control center) detects a high level of sex steriod in the blood, it shuts off release of GnRH to stop producing testersterone
Stop of steroid usage may return homeostasis back to normal, depending on the amount of consumption. Also, depends on the long and short term effect.
CIRCULATORY SYSTEM
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INFECTION
LIVER
causes hepatoxicity: poisoning of the liver, body shutdown, liver failure, makes it inpossible to process blood
PELIOSIS HEPATITIS: blood-filled cysts form in the liver. The cysts can rupture, causing internal bleeding and even death
Continuous use of Steroids leads to negative mental effect such as impaired judgement, extreme irritability and aggression, delusion, might lead to permanent health problem.
Steroid usage stop
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withdrawal symptom: Fatigue, restlessness, loss of appetite, sleeplessness, decrease in sex drive
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use of nonsterile injection techniques or share contaminated needles causes HIV and hepatitis B and, anabolic steroids may suppress the immune system, which could worsen infections.
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KIDNEY FAILURE: high blood pressure, places great amount of stress on this organ.