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Inborn Errors of Metabolism (Bilirubin Inborn Errors (Neonatal Hepatitis…
Inborn Errors of Metabolism
Bilirubin Inborn Errors
Unconjugate --> Conjugate (UGDP deficiency)
Criggler Najjar Syndrome
Type 1 SEVERE No enzyme
Type 2 DEficient enzyme
Gilbert Syndrome
No need to biopsy
Aggrevated in (excersize and starvation)
Canaliculi Transport Problems
Dubin - Johnson Syndrome
Liver Black pigmented
Asymptomatic
Rotor Syndrome
No pigment
Asymptomatic
Neonatal Jaundice
Physiological
first 2 weeks of life
Neonatal Hepatitis
Not spesific entity
Pathological
Similar to BİLİARY ATRESIA
Syncytial giant cells