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Diabetes (Type 2 diabetes (Generalities (90% of diabetes, usually after 40…

- - - - blindness
      - kidney failure
      - heart attack
      - stroke
      - amputation
- - - - vascular lesions
      - atherosclerosis
      - myocardial infarction
      - stroke
      - arteritis
      - alters kidney
      - alters retinas
- - - - Loose weight if need
      - Regular and adequate physical activity
      - Healthy diet
    - - alpha-glucosidose inhibitors
      - biguanides
      - hypoglycemic sulphonamides and glinides
      - GLP1 analogues of GLP1-blocking drugs
- - - - reduction of blood volume
      - decrease vasodilator effect of insulin
      - decrease in percentage of oxidative muscles fibers
      - alteration of muscles oxidative capacity (mitochondrial enzymes)
      - lipids metabolism abnormalities (lower use of lipids)
      - decrease muscle capillary density
  - - - glycogen storage<normal (synthase abnormalities)
      - impaired oxydative metabolism
      - reduce glycemia (hypoglycemia)
    - - unbalance between glucose production and utilisation
      - risk of hyperglycemia with hyperketonemia
  - - - strenght and muscular endurance (body composition)
      - aerobic training : VO2max and endurance oxydative metabolism (decrease in lactate production, increase lipids oxydation and glycogen reserves
    - - improve glucose tolerance
      - improve muscle glucose transport (GLUT4)
      - improve lipids profile
      - decrease cardiovascular risk factors
      - quality of life
  - - - medical certificate
      - collation
      - cardio-pulmonary effort test
      - well controlled glycemia
    - - Duration: long but not necessary continuous (45-60min)
      - Intensity 50-85% VO2max (cross over, lipox max)
      - 3 sessions/week idealy everyday
    - - duration: 8-10 stations (main musles groups)
      - intensity: 10-15 reps at 60-70% max volontary contraction
      - 2 session/week (complements)