LSD, PCP, Ketamine, and Hallucinogens
A class of drugs that leads to distortions of reality and perceptions, hallucinogens are typically broken down into two main categories: classic hallucinogens (LSD, peyote, psilocybin, DMT, Ayahuasca) and dissociative drugs (PCP, salvia, DXM, ketamine), per NIDA. It is not certain exactly how these drugs work in the brain; however, it is largely understood that they interrupt normal communication between neurotransmitters. Dissociative drugs are believed to disrupt the action of glutamate, a brain chemical that is involved with memories, cognition, emotions, and how people perceive pain.