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RBC (features (1.mature rbc is small,round & biconcave, 2.has no…
RBC
features
1.mature rbc is small,round & biconcave
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- cytoplasm contains a special pigment the haemoglobin
4.haemoglobin is a red iron rich protein that binds with O2 & gives blood its characteristic red colour.
5.its plasma membrane has a special type of cytoskeleton made up of actin & spectrin.spectrin is deformable & gives RBCflexibility & elasticity to change and resume shape as they are carried through capillaries.
function
1.main function is to carry o2 from lungs to tissues & to carry co2 ,a waste product of metabolism to the lungs ,where its excreted
2.provides buffering.Hgb is a good buffer,helps in H+ ion conc.
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clinical applications
1.rbc is usually round, bt some hereditary conditions can cause abnormal rbc production like in sickle cell anemia where rbc shape is sickle shape
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development
3.haematopoiesis occurs in 3 phases the mesoblastic,hepatic & myloid phase from gestation to adulthood
- normal count in adult male is 5 million/mm3
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- develop in the bone marrow of long bone in adults by the process erythropoiesis
4.from a pluripotent cell te haematopoietic stem cell and finally to a reticulocyte that matures into a RBC.