Please enable JavaScript.
Coggle requires JavaScript to display documents.
Neuropathic pain (Type of Pain (Chronic Pain (6 months, Peripheral…
Neuropathic pain
Type of Pain
Acute Pain
3 months
Sympathetic nervous system
Chronic Pain
6 months
Peripheral sensitization
Central sensitization
Cancer-Related Pain
Infiltration of Organs
Compression of Structures by an expanding tumor
Treatments that damage tissue
Neuropathic Pain
Trigeminal Neuralgia
Women>men
Middle-aged, Older individuals
Lesions or tumor of the brainstem
Diabetic Neuropathy
Peripheral nerves damage
Pathogenetic mechanism is unknown
Postherpetic Neuralgia
Virus
Along the nerve roots
Ischemic Pain
Cellular injury
Release of chemicals
Nociceptors
Referred Pain
Physiology of Pain
Transmission
Aδ fibers
Source
Thermal
Mechanical stimuli
Fast 5~10m/sec
Amount：10%
Sensory quality of pain mediated
Sharp
Stinging
Cutting
Pinching
C fibers
Amount：90%
Source
Mechanical
Chemical
Thermal
Slower 0.6~2m/sec
Sensory quality of pain mediated
Dull
Burning
Aching
Perception
Awareness
Sensation
Transduction
Chemical mediators
Bradykinin
Serotonin
Histamine
H+
Prostaglandin E2
K+
Permeability
Injury
Ischemia
Blood clotting
Inflammation
Necrosis
Edema, Nociceptors
Modulation
Endorphin
Enkephalins
Endorphin polypeptides
α-endorphin
β-endorphin
γ-endorphin
Opioids
Mu (μ)
Kappa (κ)
Sigma (σ)
Delta (δ)
Treatment Modalities
Interrupting
Modulating pain transmission
Altering the perception and integration
Physiologic Responses to Pain
Signs and symptoms
Vital signs
Respiratory rate fast
High Blood pressure
Heart rate fast
Dilated pupils
Nausea and vomiting
Urine retention
Pallor and perspiration
Physiologic response
Increase gastric secretions
Decrease gastrointestinal motility
Bronchioles dilate to high oxygenation
Increase circulating blood glucose
Blood shifts from superficial vessels to striated muscle, heart, lung and brain
Hypomotility of bladder and ureters