systemic lupus erythematous (multi system alteration function (hematologic…
systemic lupus erythematous
The most common pattern is a mixture of constitutional symptoms with musculoskeletal, skin, renal, and serologic involvement.
multi system alteration function
hematologic effect(leukopenia, thrombocytopenia, and hemolytic anemia)
central nervous system
skin(butterfly rash and discoid lupus)
renal system (glomerulonephritis)
heart(endocarditis and myocarditis)
for delay disease and process
anti rheumatoid drug
a genetic or familial tendency combined with hormonal and environmental influences make a person more susceptible to develop SLE
Activation of the B lymphocytes to develop autoantibodies and cytotoxic T lymphocytes, which promote inflammation and prevent organ damage
It is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Immune response by autoantibodies against a person's own tissues, cytoplasm, cell nucleus including the DNA.
Alteration of antigens that make them unable to be recognize as self. the ability to recognize self by apoptosis is altered.
Lupus is a long-term autoimmune disease in which the body's immune system becomes hyperactive and attacks normal, healthy tissue. Symptoms include inflammation, swelling, and damage to the joints, skin, kidneys, blood, heart, and lungs.
The most common clinical symptoms are fever, rash, extreme fatigue, and arthritic pain
Clinical findings may include cardiac abnormalities, neurological abnormalities, hemolytic anemia, poly arthralgia, and polyserositis.
swelling, joint pain, pericardial effusion, pleural effusion
non steroidal anti inflammatory drug
anti malarial drug to slow disease progress
immune suppressant drug