Please enable JavaScript.

Coggle requires JavaScript to display documents.

DNA AND GENE EXPRESSION (Bacterial DNA replication proteins + function.…

- - - - A polynucleotide strand has a direction it goes in, from the 5' end (with phosphate group) to the 3' end (with -OH group of sugar)
    - - Thymine (T) Guanine (G) Cytosine (C) Adenine (A)
- - - - RNA polymerase moves along the DNA template strand, joining complementary RNA nucleotides to the 3' end of the growing RNA transcript . behind the polymerase, the new RNA peels away from the template strand which reforms a double helix with the non template strand
    - - additional transcription factors bind to the DNA along with polymerase 2, forming the transcription initiation complex, RNA polymerase 2 then unwinds the DNA double helix and the RNA synthesis begins at the start point on the template strand.
      - several transcription factors, one recognizing the TATA box, must bind to the DNA before RNA polymerase 2 can bind in the correct position and orientation.
      - eukaryotic promoter commonly includes a TATA box (a nucleotide sequence containing TATA) about 25 nucleotides upstream from the transcriptional start point.
  - - - This in turn determines where transcription starts and on which of the two strands of the DNA helix is used as the template.