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Ageing (Primary hallmarks (causes) (genomic instability (accumulation of…

- - - - Damage + ageing
    - - Survival + homeostasis
- - - - damage to
        
        membranes = change in fluidity
        
        waste removal apparatus = accumulation of misfolded proteins
        
        DNA + RNA = breaks between base and sugar backbone
        
        DNA and RNA polymerase = errors in reading the template
        
        protein degradation apparatus = partially degraded proteins
        
        oxidative stress defense enzymes = accumulation of H2O2