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52 year old female with ALS (downstream (symptoms (weakness in the lower…
52 year old female with ALS
Background information
Physiology
organ system
muscular system
movement
stabilize joints
maintain posture
generate heat
nervous system
send and receive signals through the body
peripheral nervous system
connects the CNS to the limbs and organs
central nervous system
controls our breathing
controls heart rate
releases of hormones
body temperature
emotion
movement
organs
spinal cord
connects a large part of PNS to the brain
part of the CNS
main support of the body
cerebrum
interpreting touch
vision
hearing
speech
reasoning
emotions
learning
fine movement
brain
controls thoughts
movement of arms and legs
function of many organs
muscles
produce force
produce motion
posture
movement of internal organs
lungs
gas exchanges
Anatomy
Organ System
Nervous System
Peripheral Nervous System
Central Nervous System
Brain
Spinal Cord
muscular system
Organs
Brain
located in the head
serves as the center of Nervous System
Muscles
soft tissues
cardiac muscle tissue
skeletal. muscle tissue
smooth muscle tissue
Cerebrum
largest part of the brain
lungs
pair of spongy, air filled organs
spinal cord
runs along the spine
Normal Cellular Process
descending tracts
ascending tracts
the process of movement
Precentral Gyrus
Basal Nuclei
Cerebellum
downstream
organs
Brain
Mid Cognitive Impairment
Spinal Cord
lungs
shortness of breath
esophagus
difficult swallowing
muscles
muscle cramps
muscle weakness
stiff muscles
muscle spams
trouble with coordination
loss of muscle
overactive reflexes
organ systems
Nervous system
muscular system
complications most likely to be seen going forward
malnutrition
choking
pneumonia
bed sores
symptoms
cognitive behavioral changes
difficult walking
tripping or falling
weakness in the lower limbs
legs
feet
ankles
hand weakness/clumsiness
trouble swallowing
muscle cramps
twitching
upstream effect
Direct
what's causing this patients symptoms?
disease is attacking the motor neurons from the brain and spinal cord, astrocytes and oligonucleotide
Upper Motor neuron
found in the cerebral cortex and brainstem and carry information down to activate interneurons
lower motor neuron
turn directly signal muscles to contract or relax
oligonucleotides
Small pieces of DNA or RNA that can bind to specific molecules of RNA
astrocytes
specialized glial cells that outnumber neurons by over fivefold
indirect
What predisposes this patient to contracting ALS? What are some lifestyle
factors that could also contribute to her development of ALS?
age
ages between 40 and mid 60's are at higher risk for ALS
she's 52
heredity
5 to 10 percent of people with ALS inherit it
her brother died from ALS at age 31
suspects her father died from ALS
US military services
proud Gulf War veteran
studies indicate this is a higher risk for ALS
genetics
genetic testing confirmed ALS