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Lab tests show that he is infected with Clostridium tetani, a common…
Lab tests show that he is infected with Clostridium tetani, a common bacterium found in soil that can be transmitted by using dirty needles
A 23 year old male patient demonstrating severe face and arm muscle spasms was brought to the emergency department by his brother. The patient can hardly speak.
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Neuromuscular Junction
As the axon of a motor neuron approaches a muscle that it innervates, it divides into multiple branches, each of which makes a synapse called a neuromuscular junction
set of muscle fibers that contract when an action potential propagates down the branches of one particular axon is known as a "motor unit"
action potential reaches a neuromuscular junction, it causes acetylcholine to be released into this synapse.
acetylcholine binds to the nicotinic receptors concentrated on the motor end plate,
This binding causes the nicotinic receptor channels to open and let sodium ions enter the muscle fiber
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Exocytosis
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Fusion of the vesicle membrane with the cell membrane releases the vesicle contents outside the cell.
Twitch
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A twitch occurs when one muscle fiber contracts in response to a command (stimulus) by the nervous system.
Clostridium tetani
is an obligate anaerobic bacteria whose spores produce two distinct toxins—tetanolysin, which causes local tissue destruction, and tetanospasmin, which causes clinical tetanus
its spores are highly resistant and are capable of surviving boiling as well as household disinfectants.
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