Patient lab results shows he is infected with the bacteria Clostridium…
Patient lab results shows he is infected with the bacteria Clostridium Tetani.
A 23 year old male patient demonstrating severe face and arm muscle spams was brought to the E.R. Department
patient got a bacteria trough dirty needles
Got new tattoo in an unsanitary place
Patient did not receive his booster shots before getting a tattoo
spams and stiffness in your jaw muscles
the severity of the spams may cause the bones to break
stiffness in your neck muscles
severe tetanus may interfere of stop your breathing. respiratory failure is the most common cause of death.
Lack of oxygen may also induce cardiac arrest and death.
may cause other organs to not work properly because of the infection
stiffness of your abdominal muscles
rapid heart beat
high blood pressure
hear attack, or stroke
it directly affects the brain and the nervous system. It blocks the release of glycine, resulting in over-stimulation by motor neurons of the muscles and excessive muscle contractions
brain damage because of the lack of oxygen
The whole process on the events of neuromuscular junction will be affected by the toxin.
The neuromuscular juction consists of 4 steps, the excitation, excitation-coupling, crossbridge and relaxation.
A nerve triggers voltage gated channels to open, calcium enters the synaptic knob and binds to synaptic vesicles, then is released by exocytosis into the synaptic cleft. 2. The end plate potential initiates an action potential along the sarcolemma and T-tubules. ACh binding causes Na+ to rapdly enter the skeletal muscle fiber and K+ to slowly exit the skeletal muscle which results in an EPP. Calcium is release from the sarcoplasmic reticulum.
Calcium binds to troponin exposing myosin binding sites on action, myosin head and actin attached, and a power stroke motion of myosin head pulls thin filament past it.
unable to control your muscles, excessive muscle contractions
muscles spams can interfere with your breathing, hard to breath or stop breathing
body not receiving enough oxygen can lead to cardiac arrest and death
May cause pneumonia
if not treated can lead to necrosis
the bacteria can affect the heart itself and carry on the infection throughout the body
high blood pressure and increase in heart rate
A Twitch: is a single, brief contraction and then relaxation of a skeletal muscle fiber in response to stimulation
A summation: a summation of contractile forces as the effect of each new wave is added to the previous wave
A tetany, is a muscle in continuous contraction
The toxin blocks the release of glycine ( the inhibitory neurotransmitter in the spinal cord)
This inhibit the functions of the muscle,