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Obesity Trends (Lyse A. Norian, Ph.D. (Diet and Obesity: Positive and…

- - - - Over the course of cancer treatment, obesity is associated with unfavorable immune signatures in human renal tumors.
      - Decreased therapeutic efficacy is not due to differences in renal tumor size or body weight at treatment initiation.
- - - - Bodyweight is regulated by multiple systems, which may be neurologically mediated
      - After weight loss, patients were seen to have increased hunger and delayed satiety. This ideology increases the reward system when eating food, and decreases overall restraint.
- - - - Increased energy intake is a result of weight compensation, not the changes in metabolism or activity levels. This means that the direct input of energy intake is the main factor that resulted in changed weight. This can be used to better understand how people can manage, gain, or lose weight as a dietitian.
      - A study was conducted on whether liquid or solid sugar food form was preferred. The study demonstrated that the majority of people preferred the solid form of sugar. This is important because as a dietitian, knowing the way most people consume sugar can change more effectively intervene to promote a pattern for healthy eating.
- - - - Humans depend more strongly on the timing of eating. When food intake is limited to early in the day or the middle of the day it decreases hunger, reduces weight or fat mass, reduces glucose, increases fat oxidation, lowers blood pressure, and improves sleep.
      - Time-restricted feeding can improve cardiometabolic health if it is done in the right manner, per the studies provided. Meal timing per the circadian rhythm of the day promotes a better path toward weight loss and maintenance than conventional dieting.
- - - - Rats with high aerobic capacity have metabolic adaptations to high fat diets that make them protected against obesity, fatty liver, and insulin resistance. These adaptations are not found in the LCR.
      - Differences in hepatic mitochondrial content and function may play a central role in mediating the metabolic differences between the high and low aerobic capacity rats.