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Clostridium Tetani (Affected systems (Lymphatic, Circulatory, Nervous,…
Clostridium Tetani
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Toxin produced
tetanospasmin; binds to presynaptic membrane of NMJ and travels retroaxonally to inhibit acetylcholine in interneurons.
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Can cause Tetanus; infectious disease causing painful muscle contractions. Mainly in cephalic region making it hard to breathe, swallow, and open mouth.
toxin can kill many essential systems of the body and cause permanent neuron damage, muscle damage, and immune damage.
Action potential is propagated down the neurons axon when neuromuscular junction reaches threshold Acetylcholine is released by exocytosis through synaptic vesicles and recepted at the motor end plate to begin excitation.
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