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Muscle (Functions (Generating heat, Amino acid reservoir, Stabilizing…
Muscle
Functions
Generating heat
Amino acid reservoir
Stabilizing joints
Force production
Maintaining posture
Embryonal myogenesis
Gastrulation
Mesoderm
Paraxial mesoderm
somites
Dorsal part
:arrow_up: PAX3, PAX7
Dermomyotome
Delamination+ migration of muscle progenitor cells
1 more item...
Ventral part
:arrow_down: PAX3, PAX7
Sclerotome
SHH + Wnt
:arrow_up:Myogenesis
BMP
:arrow_down:Myogenesis
Structure
Muscle
Fascicle
Muscle fiber
Myofibril
Sacromere
Myofilament
Actin
Troponin
Tropomyosin
Myosin
Sarcoplasmic reticulum
T-tubules
Endomysium
Perimysium
Epimysium
Plasticity
Atrophy
FoxO
LC3 & ATG12
Autolysosome (ALP)
Murf1 & Atrogin
Proteasome (UPS)
Protein degradation
Hypertrophy
Regulator: IGF-1
Akt
eIF2
:arrow_up:Translation initiation
mTor
eLF4
:arrow_up:Translation initiation
S6
:arrow_up: Translation capacity
Repair
Atrophy
Regeneration stimulus
Satellite cell activiation
proliferation
Differentiation and fusion
Regeneration
:arrow_up:Protein Synthesis