Please enable JavaScript.
Coggle requires JavaScript to display documents.
Amyotrophic Lateral Sclerosis (ALS) (Complication (Deterioration of…
Amyotrophic Lateral Sclerosis (ALS)
Nervous sytem
Peripheral neuron
31 paires spinal cord
8 cervical
2 upper limbs
12 thorasic chest
Lumbar
2 Lower limbs
5 Sacral & coccyged
Urinary and digestive system
Genital organ
Lower limbs
Central Nervous System
Spinal cord, Long, tubular nervous structure extends from medulla oblongata in the brain stem to lumbar area of vertebral column.
Sensory: Ascending tract to brain
Spinothalamic tract
Pain
Temperature
Crude, light, touch
Post column
Position
Vibration
Fine touch
Motor Descending Tract
2 Pathways
Pyramidal or Corticospinal
Muscle
Voluntary movement involving skill and purpose
Extrapyramidal
Lower motor neuron
Maintenace of muscle tone
Body control
Nerve layer
Endoneurium- Layer that surrounds single axon
Epineurium-Outer layer and is continuous with dura matter
Perineurium- layer that surrounds a fascicle or bundle of axons
Branch of spinal nerves
Ventral ramus
Grey ramus
White ramus
Dorsal ramus
Pia matter: Connective tissue covering/surrounding the spinal cord
Arachnoid matter: Filled with cerebrospinal fluid
Dura matter: Connective tissue that surrounds brain and spinal cord
White matter funiculi: Contains bundles of axons in the white matter
Grey matter: Contains central and somas/cell bodies surrounding the central canal
Sensory nuclei
Motor nuclei
Posterior grey horn
Lateral grey horn Gray commissure
Anterior grey horn
White matter: Consists of axons, nerves are organized into tracts,
Sensory nerve tracts
Motor nerve tracts
Filum terminale: Fibrous tissue that acts as an anchor to the spinal cord
Conus medullaris: Tapering or cone shaped
Plexus
Cervical plexus: Head, neck, shoulders
Cervical plexus: Head, neck, shoulders
Brachial plexus
Chest
Shoulders
hands
Arms
Lumbar plexus
Knees
Abdomen
Calves
Thighs
Brain
Brain stem
Cerebellum
Diencephalon
Cell death
Oxydative domage
Mitochondria dysfunction
Defection in axonal transport
Glutamate excitotoxicity
Aggregation of abnormal protein
Cerebrum
Complication
Deterioration of ambulation
Wheel chair
Massage
Physical therapy
Aspiration pneumonia
Antiemetic
Antibiotic
Suction of secretion and emesis
Respiration Insuffisant
Oxygenotherapy
Mecanic Ventilation
Tracheotomy
Pressure ulcer
Turning or mobilize patient every 2 hours
Apply warm compress
Deep vain thromboses pulmonary emboli
Traitement
Antithrombotic
Heparin
Wafarin
Progressive inability to perform activity of daily living
Utensils for self feed
Malnutrition
home care nurse or nurse assistant
Direct cause
Familial
Inherit Gene Mutation
Neuron degeneration
Brain to spinal
Spinal cord to the muscle
Sporadic
Anyone
Indirect cause
Rist Factor
Environmental factors
Smoking
Environmental toxin exposure: like lead
Military exposure
Metal
Chemical
Traumatic injaries
Viral infection
Intense exertion
Biological factors
Genetic gene variation
Hereditary 5-10% of ALS
Sex more man before 65 but the difference disappear after 75
Risk with age high after 40