Please enable JavaScript.

Coggle requires JavaScript to display documents.

Pulmonary Fibrosis (Viva (Ix (Blood (FBC: anaemia exacerbates dyspnoea,…

- - - - PEFR
      - ECG: RVH
    - - FBC: anaemia exacerbates dyspnoea
      - ABG: ↓PaO2, ↑PaCO2
      - IPF: ↑ESR, ↑CRP, ANA (30%), RF (10%), ↑Ig
      - EAA: +ve se precipitins
      - CTD: C3/C4, CCP (RF, ANA), scl-70, centromere
      - Sarcoid: se ACE, Ca2+
    - - CXR: reticulonodular shadowing, ↓ lung volume
      - HRCT: fibrosis, Honeycomb Lung
    - - ↓TLC¸ ↓RV, ↓FEV and ↓FVC
      - FEV1:FVC >0.8
      - ↓ transfer factor
    - - Echo: PHT
      - BAL: may indicate disease activity
        ↑ lymphocytes > PMN: better prognosis
      - Lung biopsy: usual interstitial pneumonia
  - - - Stop smoking: single most beneficial strategy
      - Pulmonary rehabilitation
      - LTOT
      - Symptomatic Rx
        
        Anti-tussives: e.g. codeine phosphate
        
        Heart failure: diuretics, β-B, ACEi
  - - - Pred + AZA + NAC → ↑ mortality: trial arm stopped
      - NAC alone: trial arm still running
- - - - Clubbing
      - Cushingoid
      - No sputum
      - Tachypnoea, central cyanosis
    - - RA: rheumatoid hands, nodules
      - SS
        
        Sclerodactyly, calcinosis
        
        Microstomia, beak nose, telangiectasia
      - SLE: malar rash
      - AS: kyphosis
      - Sarcoidosis: EN
      - Radiation: tattoos on chest
  - - - Cor pulmonale
      - Specific cause: e.g. RA hands or sclerodactyly
      - Cyanosis
    - - Bronchiectasis
      - Chronic lung abscess
- - - - Bleomycin, Busulfan
      - Amiodarone
      - Nitrofurantoin
      - Sulfasalazine
      - MEthotrexate