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Lung Cancer (Key facts (Ix
( Staging
(CT: neck, thorax,…
Lung Cancer
Key facts
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Complications
Paraneoplastic
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Endo
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Serotonin → carcinoid (flushing, diarrhoea)
PTHrP → primary HPT (↑Ca2+, bone pain) – SCC
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Metastatic
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Confusion, fits, focal neuro
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Ix
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CT: neck, thorax, upper abdo ± brain
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Thoracoscopy, mediastinoscopy + LN sampling
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FBC: anaemia, ↑WCC if consolidation
U+E: ↓ Na (SIADH or Addison’s)
LFTs: deranged LFTs 2O to liver mets
Bone profile: ↑ Ca2+ (bone mets, ↑PTHrP)
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Mx
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NSCLC
Surgery
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Wedge resection, lobectomy, pneumonectomy
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Palliative Care
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Radiotherapy: haemoptysis, bone or CNS mets
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Exam
Complications
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SVCO
Plethoric, oedematous face and upper limbs
Dilated neck and chest veins
Stridor
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Chest
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Collapse
Tracheal deviation towards lesion
↓ expansion
PN: dull
Auscultation
↓ or absent AE
± crackles
↑ VR
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