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23 year old male has severe face and arm muscle spasms Was brought to the…

- - - - Single contraction
        
        In response to short stimulation
      - Contraction phase
      - Relaxation phase
    - - Increases force of contraction
      - Increasing the frequency of the stimulus
      - Stimuli are added together
      - Produce a stronger muscle contraction
    - - Fusion of contractions
      - Produces a continuous contraction
      - Sustained contraction
      - Occurs when the frequency of stimulation is rapid
      - No relaxation
  - - - Cell to the cell membrane
    - - Fusion of the vesicle membrane
        
        Cell membrane releases vesicle contents
        
        Outside of the cell
  - - - Down its axon
    - - Acetylcholine (ACH) into synaptic cleft
  - - - Synaptic receptors
      - ACH breakdown
        
        Via esterase
    - - Maybe Na+/ K+
  - - - Tetanolysin
        
        Causes local tissue destruction
      - Tetanospasmin
        
        Causes clinical tetanus
    - - Locked jaw
      - Spasm of the jaw muscle
      - Stiffness of the neck
      - Starts from neck then goes to back
- - - - Or needle not being sterilized good enough
    - - Puncturing the skin
  - - - Effects the central nervous system
      - The poison blocks nerve signals
        
        From spinal cord to your muscles
        
        Leads to severe muscle spasms