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Patient presents with infected tattoo and is having symptoms of muscle…

- - - - contains dermis, epidermis, hypodermis
        
        affected because getting a tattoo is injecting ink directly into the dermis
    - - contains neurotransmitters that allow our body to send and receive signals
        
        affected by tetanus because it can inhibit the body's ability to send and receive these signals
    - - composed of lungs, trachea, and other breathing organs
        
        affected by Tetanus because the infection can inhibit this system from working
    - - contains skeletal muscles that allow for locomotion
        
        directly associated with nervous system
        
        tetanus affects this because the body cannot properly tell the muscles how to move
  - - - chemically gated ion channels
        
        opened by chemicals such as neurotransmitters
      - voltage gated ion channels
        
        open or close in response to voltage changes in membrane potential
  - - - Axons
        
        threadlike extensions from the motor neuron
        
        travel from CNS to skeletal muscle
      - Neuromuscular Junction
        
        axon branches on an end of a muscle fiber
      - Axon terminal
        
        end of an axon
      - motor end plate
        
        highly excitable region of the sarcolemma in closest proximity to the axon terminal
  - - - ACh released from motor neuron
      - Na+ diffuses into muscle fiber
      - interior becomes less negative (more positive)
      - results in local depolarization (called end plate potential)
    - - voltage-gated Na+ channels will open
      - large influx of Na+ triggers AP that is unstoppable and will lead to muscle fiber contraction
      - AP spreads across the sarcolemma, causing the area to depolarize
    - - Na+ voltage gates close
      - voltage-gated K+ channels open
      - K+ influx brings cell back to initial resting membrane potential
      - ionic conditions are restored by the Na+ K+ pump
  - - - progresses to fixed rigidity of the jaw
      - trunk/limb spasms
      - usually fatal due to failure of respiratory sytem
  - - - simplest contraction resulting from a muscle fibers response to a single action potential
    - - results if two stimuli are received by a muscle in rapid succession
    - - muscle cramps caused by overly stimulated nerves