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Reagent + Substrate (Nucleophile only (1° (Sn2), 2° (Sn2), 3° (Sn1)),…

- - - - Sn2 predominates unless t-BuOK is used as reagent in which case E2 predominates
  - - - E2 predominates because E2 is not sterically sensitive. Sn2 is extremely sensitive to steric consideration
  - - - Only E2 because Sn2 is too sterically hindered
- - - - Not practical because reaction is too slow
  - - - Not practical because the reactions are too slow and many products are formed.
      - 2 ° Alcohols will undergo an E1 reaction when treated with Sulfuric acid and heat
  - - - High temperature favors E1.
      - 3 ° alcohol will undergo an E1 reaction when treated with sulfuric acid and Heat