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brain (acute brain injury (ICP (ICP↑ (headache, Vomiting, altered level of…

- - - - cell hypoxia
        
        mitochondrial failure
        
        mitochondrial sequestration of Ca2+
        
        calcium overload
        
        free radical production
        
        cell death
        
        ↓ATP production
        
        ↓Calcium pumping
      - reperfusion
        
        immune cells
      - ↑Glutamate release
        
        open NMDA channeis
  - - - headache
      - Vomiting
      - altered level of consciousness (drowsiness)
      - blurry vision
- - - - IICP,
        
        lead to herniation and death.
- - - - treament：supportive
- - - - treatment：clipping or placement of endovascular coils for embolization
- - - - treatment：Supportive and symptomatic