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Anti-Depressants (Venlafaxine (MOA SNRI
2nd line anti-depressant, SE
HTN…
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Anti-Depressant Extras
Serotonin Syndrome
Cognitive
headache, agitation, confusion, coma
Autonomic
sweating, ↑HR, palpitations, HTN, hyperthermia
Somatic
myoclonus, clonus, hypertonia, tremor
Monoamine Oxidase
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MAO-A: adrenaline, norad, serotonin, tyramine, dopamine
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TCA Toxicity
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Sx
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CNS: hypertonia, hyperreflexia, extensor plantars, seizures
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