Please enable JavaScript.
Coggle requires JavaScript to display documents.
Anti-Parkinsonian Drugs (Levodopa (SE
Dyskinesia
On-Off phenomena
…
Anti-Parkinsonian Drugs
Levodopa
-
-
-
Interactions
- fx ↓d by antipsychotics
- HTN crisis with non-selective MAOIs
- Anti-HTNs enhance ↓BP fx
- Food (protein) affects absorption
-
Selegiline
Rasagiline
MOA
Selective MAO-B inhibitors
Prevent intraneuronal degradation
of Da
Buccal preps → better bioavailability
-
-
-
-
-
-
-
Parkinson’s Disease
Medical
-
-
Response Fluctuations
-
COMT inhibitor: tolcapone, entacapone
-
-
-
Adjunctive Therapies
-
-
Atypical antipsychotics: e.g. quetiapine, clozapine
-
SSRIs: citalopram, sertraline
-
General
MDT: neurologist, PD nurse, physio, OT, social worker, GP and carers
-
-
-
-