Please enable JavaScript.

Coggle requires JavaScript to display documents.

Other Antibiotics (Anti-TB drugs (Isoniazid (SE Peripheral neuropathy …

- - - - Rifampicin
        Rifaximin
        Rifabutin
        
        Also used in
        Legionella
        Prophylaxis meningits
        
        CI Jaundice
        
        SE
        Yellow secretions
        Hepatitis
        
        Rifaximin has v. poor oral
        absorption and is used in
        hepatic encephalopathy
        
        P450 inducer
        
        W-
        
        ↓OCP
        
        ↓AEDs
  - - - ↑ risk of SEs if slow
        acetylator
        Give with pyridoxine
- - - - Use
        Anaerobes
        GI sepsis
        Aspiration pneumonia
        AAC
        H. pylori
        PID
        Protozoa:Giardia
      - SE
        Metallic taste
        GI upset
        Metro: gynaecomastia
      - Avoid EtOH
        Disulfiram-like
        reaction
        
        Aldehyde dehydrogenase
        inhibitor
- - - - Stop immediately if rash or
        dyscrasias occurs.
- - - - Use
        Broad spectrum: esp. Gm-
        GI infections: campy, shig…
        Pseudomonas: esp. in CF
        Prostatitis, PID
        Anthrax
      - SE
        ↑ QTc
        GI upset
        Tendonitis ± rupture
        ↓ seizure threshold
        Photosensitivity
      - P450 inhibitor
        Antacids ↓absorption
      - CI in pregnancy
- - - - Use
        Aerobic and anaerobic Gm+
        MRSA
        HAN
        Infective endocarditis
        AAC (PO)
      - SE
        Nephrotoxic
        Hypersensitivity rash
        Neutropenia
        Ototoxic
        
        tinnitus
        
        SNHL
      - CI
        ↓ dose in renal
        impairment
      - Must monitor levels
        
        pre-dose trough