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Anti-Virals (Cidofovir (MOA
Inhibits viral DNA polymerase
No activation…
Anti-Virals
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CMV Tx
- retinitis
- pneumonitis
- CMV prophylaxis
HHV-6 Tx
Ganciclovir
MOA
2-deoxyguanosine analogue
Phosphorylated to dGTD analogue by viral UL97
Triphosphate competitively inhibits viral DNA pol
IV only
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