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Resp Bacterial Infections (TB (2mo: RHZE, 4mo: RH, Give pyridoxine 20mg OD…
Resp Bacterial Infections
Pneumonias
HAP
Mild / <5d: Co-amoxiclav 625mg PO TDS for 7d
Severe / >5d: Tazocin for 7d
± vanc for MRSA
± gent for Pseudomonas
Aspiration Pneumonia
Co-amoxiclav 625mg PO TDS for 7d
CAP
Mod
amoxicillin 500mg TDS and clarithro 500mg BD PO/IV for 7d
clarithro alone if pen allergy
Sev
Co-amoxiclav 1.2g TDS IV / cefuroxime 1.5g TDS IV AND clarithro 500mg BD IV for 7-10d
Add fluclox if staph suspected
Mild
amoxicillin 500mg TDS PO for 7d or
clarithro 500mg BD PO for 7d
Atypical
PCP
Co-trimoxazole
Legionella
Clarithro + rifampicin
Chlamydia
tetracycline
Legionella
Levofloxacin
OR Clarithromycin + rifampicin
PCP
1st: co-trimoxazole
2nd: pentamidine
Exacerbation of COPD
Rx if ↑ sputum purulence c¯ ↑sputum volume or ↑ dyspnoea or consolidation on CXR
Amoxicillin 500mg PO TDS for 7d
Or, doxy 200mg STAT + 100mg BD for 7d
TB
2mo: RHZE
4mo: RH
Give pyridoxine 20mg OD throughout Rx
Longer Rx if resistant organisms or extra-pulmonary TB