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Brain (Nervous system (CNS (Neuronal Structure and Function (Phagocytic,…
Brain
Nervous system
ANS
PNS
CNS
Neuronal Structure and Function
Phagocytic, maintaining the CSF brain barrier
Presynaptic neuron- Cell body- Poslsynaptic neuron
Cell body, Dendrites, Axon
Glutamate, Dopamine, Norepinephrine, Serotonin
Glucose for production of ATP
Brain Structural
and Organization
Mechanism of Brain Injury
Ischemic Stroke
IICP
ICP >15mmHg
CSF, Blood, Tissue unbalance
Headache, Vomiting, Blurry Vision, Consciousness decreases, Pupil change, Altered respiratory patterns
Thrombotic , Emboli
5~10 mins of complete occlusion-Brain damage
Glutamate release increase, open NMDA channels
Mitochondrial failure
ATP production and Calcium pumping down
sequestration of CA+
calcium overload
Cell death
Mallformation
Cerebral aneurysm, AVM
Hemorrhagic Stroke
TBI
Spontaneous
Central nervous system infection
Encephalitis
Meningitis
Viruses, Bacteria, Fungi, Parasites
Supportive care, antibacterial drug
Headache, fever, stiff neck
Brain abscess
Assessment
GCS
12 cranial nerves