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Sex Hormones (COCP (Cautions and Contraindications (VTE Risk: caution if 1…

- - - - FHx of VTE
        
        BMI >30, avoid if >35
        
        Long-term immobilisation
        
        Hx of superficial thrombophlebitis
        
        35yrs, avoid if >50yrs
        
        Smoking
    - - FHx of arterial disease
        
        DM
        
        HTN
        
        Smoking, avoid if >40/d
        
        over 35yrs, avoid if >50yrs
        
        Migraine w/o aura, avoid if migraine with aura
  - - - Contraception
      - ↓ dysmenorrhoea, ↓ menorrhagia
      - ↓ PMT
      - ↓ benign breast disease
      - ↓ ovarian and endometrial Ca
      - ↓ risk of PID
  - - - ↑ risk of VTE
      - Small ↑ risk of breast Ca
      - Small ↑ risk of IHD
      - Gallstones
      - Cholestatic jaundice
      - Breast tenderness
      - Hepatoma
- - - - ↓ urinary frequency / urgency
      - ↓ risk of bowel Ca
      - ↓ risk of osteoporotic #s
      - ↓ hot flushes, ↓ vaginal dryness, ↑libido
  - - - ↑ risk of Ca: breast, endometrial, ovarian
      - ↑ risk of VTE
      - ↑ risk of stroke and IHD
      - Cholestatic jaundice
  - - - Oestrogen-dependent Ca
      - Hx of breast Ca
      - UnDx vaginal bleeding
      - VTE
- - - - n/v
      - Headache
      - ↑ wt.
      - Breast tenderness