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Patient arrives with face/arm muscle spasms. Patient recently got a…

- - - - vesicles transported to the cell membrane through micro-tubules
        
        movement of vesicles are powered by motor proteins
        
        dyneins
        
        myosins
        
        Kenesins
    - - vesicle gets linked & pulled into contact of cell membrane
    - - attachment of vesicle membrane with the cell membrane
        
        Phospholipids bi layers of vesicle membrane & cell membrane begin to merge
    - - signaling processes that trigger exocytosis to take place
    - - complete fusion
      - kiss-and-run fushion
  - - - ACh diffuses, binds to its receptors, and triggers muscle action potential.
    - - Acetylcholinesterase destroys ACh so more action potential's don't arise.
    - - Nerve impulse arrives at axon terminal of motor neuron and triggers release of acetylcholine.
    - - AP traveling along t tubules open Ca2+ (calcium ion) channels in the SR , the calcium enters into sarcoplasm
    - - Ca2+ binds to troponin
    - - Contraction
    - - Ca2+ channels close and calcium transport pumps use ATP to restore low levels of calcium in sarcoplasm
    - - Troponin complex returns to original position to block myosin binding sites on actin.
    - - Muscles relaxes
  - - - Pulling actin filaments toward toward center (requires ATP)
    - - shifting actin filaments
        
        exposes binding sets
    - - Shifts actin filaments to original position
        
        Blocking binding sets
  - - - Involuntary muscle
    - - Involuntary muscle
    - - Voluntary muscle
  - - - Occurs as successive stimuli are added together to produce a stronger muscle contraction
    - - Medical sign consisting of involuntary contraction of muscles
    - - Single rapid contraction and relaxation of muscle fiber or group of muscle fibers
  - - - Medication
        
        Valium
        
        Muscle relaxants
    - - Skeletal muscle
        
        Contributes to maintaining body temp.
      - Growth
        
        Physical training alters the appearance and changes muscles performance
      - Contributes to muscle and blood flow
        
        Aerobic metabolism
        
        slow twitch fibers allow to maintain contractions over long periods of time
    - - Protein
      - Carbohydrates
      - Fat