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Lecture 2 (Streptococcal Respiratory Disease (Pharynitis (sore throat and…
Lecture 2
Streptococcal Respiratory Disease
Pharynitis
sore throat and difficulty swallowing
absence covering tonsils
Laryngitis
Bronchitis
occur when infection is spread to lower respiratory
bacterial pharyngitis
scarlet fever
Caused by group A streptococci
rheumatic fever
spread via respiratory drops
occurs mostly in winter and spring
antibodies against one strain of m protein don't help another
Enzymes
M Protein
inhibition of complement component C3b
Hyaluronic Acid Capsule
Camoflage
Streptokinases
breaks down blood clots
pyrogenic toxins
stimulate leukocytes to release cytokines that stimulate fever rash and shock
C5a peptidase
breaks down c5a
streptolysins
lyse RBC, WBC and platelets
Diphtheria
immunization brought deadly childhood disease under control
pseudomembrane obstruct airways
caused by corynebacterium diptheriae
produces toxin directly linked to symptoms
leading cause of death among unimmunized children
immunization effective prevention method