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Penicillins (Narrow Spectrum (G (given parenterally, NEVER IV), V (PO),…
Penicillins
Narrow Spectrum
G
given parenterally
NEVER IV
V
PO
Gram + abx
Last 1 to 5 days depending
Beta-Lactamase resistant penicillin
methicillin
oxacillin
dicloxacillin
floxacillin
Use with caution
upsets gut flora
exotic hindgut fermenters can die
Broader spectrum
semi-synthetic
exampled
amoxicillin
amoxi-tabs and drops
Ampicillin
polyflex
Ticaricillin
Methicillin
Potentiated penicillin
chemically combined with another drug to enhance effects of both
amoxicillin + Clavulanic acid (Clavamox)
binds to beta lactamase to prevent the betalactam ring from being destroyed
beta lactam structure that interferes with bacterial cell wall synthesis
units/mL
Cell wall agent
some bacteria produce beta-lactamase that destroys the beta lactam structure