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primary immunodeficiency (10 warning signs suggested to recognize PID in…

- - - - measurement of antibodies level in blood serum
      - B cells count
    - - respiratory burst assay
      - differential WBC count
      - CH50 test
- - - - deficiency of ADA will result accumulation of adenosine that will be converted into deoxyribonucleotide by ribonucleotide reductase, this enzyme will be inhibited by high dATP level which mean it inhibit DNA synthesis in (lymphocytes) thus no proliferation of stem cells
  - - - deficiency in HGPRT result in increase PRPP and free hypoxanthine and guanine thus increase catabolism which result in increase uric acid in blood
        
        lesch nehan syndrome
- - - - ADA deficiency
        
        autosomal recessive
      - ILR2G mutation
        
        X-linked
- - - - not money involved
      - the organ is successfully transplanted
      - organs that are essential to survive cannot be donated
  - - - except the renewed organs
- - - - first vaccine which is influenza A and B is given after 3 months of implantation
- - - - Dubai health authority
      - ministry of health and prevention
      - AbuDhabi health services company