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Nueromuscular Junction (If the toxin remains in the body what will happen…

- - - - stimuli on one nerve
    - - stimuli from several fibers
- - - - trafficking
        
        vesicles are transported to the cell membrane
      - tethering
        
        the vesicle then becomes linked to the cell membrane when it has entered
      - docking
        
        the attachment where the cell membrane and the vesicle begin to merge
      - fusion
        
        complete fusion
        
        the vesicle fully fuses to the cell membrane with the help of ATP
        
        kiss-and- run fusion
        
        the vesicle temporarily fuses to the cell membrane long enough to create a fusion pore and release its contents
  - - - trafficking
        
        vesicles are transported to the cell membrane
      - tethering
        
        the vesicle then becomes linked to the cell membrane when it has entered
      - docking
        
        the attachment where the cell membrane and the vesicle begin to merge
      - priming
        
        specific modifications that are made to trigger the exocytosis process
      - fusion
        
        complete fusion
        
        the vesicle fully fuses to the cell membrane with the help of ATP
        
        kiss-and-run fusion
        
        the vesicle temporarily fuses to the cell membrane long enough to create a fusion pore and release its contents
- - - - the synaptic end bulb triggers the release of ACh then diffuses through the synaptic cleft
      - the ACh receptors bind and activate
      - the muscle action potential is generated
      - the ACh is then broken down by an enzyme called AChE
- - - - no pathological activity
    - - enters the nervous system by the lower motor neuron and it travels to the brain and spinal cord
        
        causes jaw tightness and muscle spasms