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A 23 year old male patient demonstrating severe face and arm muscle spasms…
A 23 year old male patient demonstrating severe face and arm muscle spasms who can hardly speak. The blood test result confirms this patient is infected with clostridium tetoni,
Background
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Physiology
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Summation is the additive effect of several electrical impulses on a neuromuscular junction which collectively can generate a response.
Excitatory postsynaptic potential (EPSP) makes the postsynaptic neuron more likely to fire an action potential.
Inhibitory postsynaptic potential decreases the chances that the postsynaptic neuron will send a signal.
Upstream Causes
Direct Causes
Tetanus toxin produced by clostridium tetani which blocks the release of inhibitory neurotransmitters at the neuromuscular junction.
Indirect Causes
Puncture wounds from splinters, body piercings, tattoos and injection drugs etc.
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