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patient with Clostridium tetani (voltage gated cation channels are…
patient with Clostridium tetani
Body systems effected/involved
muscular system
cardiovascular system
skeletal system
nervous system
Clostridium tetani directly effects the neurotransmitter
being moved by the contractions
the bacteria is passed through the blood
is the main system being effected visually by being involuntary contraction
neuromuscular junction
action potential arrives at axon terminal of motor neuron
voltage gated Ca2 channels open. enters the axon terminal moving down its electrochemical gradient
causes ACH to be released by exocytosis
ACH diffues across the synaptic cleft and binds to ACH receptors on the sarcolema
opens ion channels for sodium and potassium
acetylcholine is the main neurotransmitter in muscle contraction
voltage gated cation channels are stimulated
synaptic vesicles release acetylcholine
motor neuron action potential
twitch
a single contration
has a latent period, a contraction phase, and a relaxation phase
summation
successive stimuli
not full relaxtion
produce stronger muscle
tetany
fusion of contractions to produce a continuous contraction.
tetanospasmin blocks the ACh recpetors and causes stiffness and spasms
experiencing spasms from toxins produced by Clostridium tetani
used a dirty tattoo needle
first symptom is lockjaw
stiffness of neck
high blood pressure
the uncontrollable contractions spread to vital organs like the lungs leading to death