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A 23 year old male patient demonstrating severe face and arm muscle spasms…
A 23 year old male patient demonstrating severe face and arm muscle spasms was brought to the emergency department by his brother. Lab tests show that he is infected with Clostridium tetani, a common bacterium found in soil that can be transmitted by using dirty needles. The patient was never vaccinated against this bacterium. Clostridium tetani produces a toxin that affects neurons and their ability to release neurotransmitters. The worried brother asks you what is going on?
background
systems involved
nervous
3 main functions
sensory
function
involves collecting information from sensory receptors that monitor the body's internal and external conditions.
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motor
function
Once the networks of interneurons in the CNS evaluate sensory information and decide on an action, they stimulate efferent neurons
Efferent neurons
carry signals from the gray matter of the CNS through the nerves of the peripheral nervous system to effector cells
effector
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The effector may be smooth, cardiac, or skeletal muscle tissue or glandular tissue.
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circulatory
function
is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment
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respiratory
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organs
lungs, which carry out this exchange of gases as we breathe.
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The steps involved in exocytosis,
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3)Fusion of the vesicle membrane with the cell membrane releases the vesicle contents outside the cell.
types of constitutive exocytosis,
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Neurotransmitters involved in triggering muscle contraction,
acetylcholine
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causes muscles to contract,
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If Clostridium tetani spores are deposited in a wound, the neurotoxin interferes with nerves that control muscle movement.
The infection can cause severe muscle spasms, serious breathing difficulties, and can ultimately be fatal.
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treating muscle spasms
Anticonvulsants, such as diazepam
Muscle relaxants, such as baclofen
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Ventilator
Some patients may need ventilator support to help with breathing if their vocal cords or respiratory muscles are affected.
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