Please enable JavaScript.
Coggle requires JavaScript to display documents.
Patient demonstrating severe face and arm muscle spasms (Organ systems…
Patient demonstrating severe face and arm muscle spasms
Infected with Clostridium tetani, a common bacterium found in soil that can be transmitted by using dirty needles.
Has many tattoos including a fresh one on his shoulder.
Got tattoo yesterday, from sketchy tattoo parlor
The patient was never vaccinated against this bacterium
Organ systems
Muscular system
Skeletal system
Integument system
Nervous system
Exocytosis
Vesicles are transported from within the cell to the cell membrane.
Vesicle membrane attaches to the cell membrane.
Vesicle membrane fuses with the cell membrane, releases contents outside the cell.
Neuromuscular Junction
Action potential travels from neuron to axon terminal
Voltage gated Ca+ terminal opens, diffuse Ca+ into terminal
Synaptic vesicles release Acetylcholine(a
neurotransmitter
) by exocytosis
Acetylcholine diffuse across synaptic cleft, binds to Acetylcholine receptors
Ligand gated cation channels open
Na- ions enter, K+ ions leave the muscle fiber, causing membrane potential to become less negative
Action potential propagates once membrane potential reaches threshold value
Differences
Twitch(single contraction)
Summation-successive twitches added together to produce a stronger muscle contraction.
Tetany- the fusion of contractions to produce a continuous contraction.
Clostridium tetani
Causes local tissue destruction
Painful muscle spasms
Lockjaw
Rigidity