Please enable JavaScript.

Coggle requires JavaScript to display documents.

CASE: A 23 year old male patient demonstrating severe face and arm muscle…

- - - - Jaw cramping
      - Trouble swallowing
      - Painful muscle stiffness
      - Changes in blood pressure and heart rate
      - Sudden, involuntary muscle tightening
      - Fever, sweating, and Headache
  - - - tetanospasmin
        
        causes clinical tetanus
      - tetanolysin
        
        causes local tissue destruction
- - - - how the bacteria enters the body
    - - immune system attacts the bacteria
    - - affects how the muscle contacts
    - - neurons get attacked by bacteria
  - - - set of muscle fibres that contract when an action potential propagates down the branches
        
        Action potential reaches a neuromuscular junction, causes acetylcholine to be released into this synapse
        
        acetylcholine binds to the nicotinic receptors
        
        This binding causes the nicotinic receptor channels to open and let sodium ions enter the muscle fibre.
        
        The action potential, from Na will travel down to the T-tubules
        
        Once it reached to T-tubules, SR releases Ca
  - - - The phospholipid bilayers of the vesicle membrane and cell membrane begin to merge
    - - the vesicle becomes linked to and pulled into contact with the cell membrane
    - - Vesicles are transported to the cell membrane along microtubules of the cytoskeleton
  - - - ACH
        
        controls the contraction of all skeletal or voluntary muscles
  - - - occurs because the second stimulus triggers the release of more Ca ions
        
        which become available to activate additional sarcomeres while the muscle is still contracting from the first stimulus.
    - - the stimulus frequency is so high that the relaxation phase disappears completely,
        
        contractions become continuous
    - - involves small muscle contractions in the body
        
        minor muscle contractions in the area, or uncontrollable twitching of a muscle group that is served by a single motor nerve fiber.