Severe face and arm muscle spasms

Getting a new tattoo recently

Muscular system

Nervous system

Integumentary system

Movement of body

Maintains posture

Circulation of blood

Transmits signals between different parts of the body

Protection of the body from the outside world

Respiratory system

Allows us to breathe

Chain of events

Neurotransmitters:

Exocytosis

Clostridium tetani

Muscle is stimulated by somatic motor neurons

Axon travels from nervous system to skeletal muscle

Axon divides into branches

Axon branches end on muscle fiber- forms neuromuscular junction

Synaptic bulb (house synaptic vesicles)

Synaptic vesicles are filled with acetylcholine(ACh)

Voltage gated Calcium channels are embedded in the plasma membrane of synaptic bulb

Calcium comes into the s. bulb- flows down the concentration gradient

If the channel is opened, it signals a neuron action potential

Sodium enters into muscle cell and potassium leaves.

This causes depolarization- "Zap"

Outflux of potassium

Inside of sarcolemma returns to resting potential of -70mV "repolarization"

Acetylcholine

Twitch, summation, and tetany

Twitch:

Isolated muscle contraction

Summation:

Increase contractile strength; no relaxation

Tetany:

Stays contracted: no relaxation

Vesicles transported to cell membrane

Vesicle membrane attaches to cell membrane

Fusion of membrane to membrane release the contents outside the cell

Anaerobic bacteria

Produces tetanolysin- local tissue destruction

Produces tetanospasmin- causes clinical tetanus

Cause servere muscular spams

tetanus toxin blocks the release of neurotransmitters

Can cause death by respiratory muscle failure

Muscular:

Muscle spasms

Stiff muscles

Respiratory:

Lack of breathing

Shortness of breath

Whole body:

Fever

HTN

Nervous sys dysfunction

sweating

Rapid heart rate