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all introns and extrons initially transcribed into RNA (introns (4 major…

- - - - self splicing
    - - self splicing but mechanism diff form group I introns
    - - spliceosomal (slicing requires small nuclear RNAs and # of proteins)
    - - enzymatic
- - - - determined the point at which cleavage will take place
        
        sequences rich in uracil is typically downstream of the cleavage site
- - - - methyl groups added to the 5' end. first of these methyl groups is added to position 7 of the base of the terminal guanine nucleotide making the base 7-methylguanine
- - - - upstream of the first codon translated into an amino acid (start codon)
- - - - short consensus sequences
    - - adenine nucleotide 18-40 nucleotides upstream of the 3' splice site
      - weak consensus sequence
      - between 5' and 3' splice sites, apart of the intron
    - - each RNA molecule components are small nuclear RNAs (snRNAs)
        
        the snRNAs associate w/ proteins to form snRNPs (small nuclear ribonucleoprotein particles)
        
        each snRNP contains a 1. single snRNA mol 2. multiple proteins
      - spliceosome- proteins +snRNAs (each snRTP has= 5 snRTP + proteins)
        
        1 snRTP= U1, U2, U4, U5, U6