Please enable JavaScript.
Coggle requires JavaScript to display documents.
EOSINOPHILS (Activated via Cytokines (IL-5, C3b, IgA, IgG, Presence of…
EOSINOPHILS
Connective Tissues
Underlying respiratory
GI/GU Tracts
Granular Cytoplasm
Contains preformed mediators
Activated Eosinophils
Release Granule Contents
Enzymes
Eosinophil Peroxidase
Collagenase
Toxic Proteins
Major Basic Protien
Eosinophil Cationic Protein
Eosinophil-derived Neurotoxin
Activated via Cytokines
IL-5
C3b
IgA
IgG
Presence of FceR is controversial
Synthesise
Cytokines
IL-3
IL-5
Stimulates Eosinophil Production
In Bone Marrow
GM-CSF
Chemokines
IL-8
Lipid Mediators
Leukotrienes
PAF
Eotaxin
Promotes Eosinophil Migration
Promotes Activation