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23 year old male with Clostridium Tetani (Respiratory (breathing problems…
23 year old male with Clostridium Tetani
Direct
neuron releases acetylcholine (ACh) and that is what begins muscle contraction
A enzyme called Acetylcholinesterase breaks up ACh, but if it doesn't the muscle will continue to spasm until it is broken down
Indirect
got a tattoo from a "sketchy" tattoo parlor , with a dirty needle
Got a infection from that dirty needle
Respiratory
breathing problems due to spasms of the vocal cords
spasms of the muscles that control breathing
pneumonia
Nervous
Brain damage (from lack of oxygen)
Cardiovascular
abnormal heart rhythm
Skeletal
bone fractures and fractures of the spine (results from muscle spasms and convulsions)
Lymphatic
secondary infections (due to prolonged hospital stays)
Muscular
severe muscle spasms
Background Information
Anatomy
Normal structures malfunctioning
Muscular system
Skeletal, smooth, and cardiac muscle
Respiratory system
Larynx, lungs
Structural classifications of neurons
Unipolar
Bipolar
Multipolar
Physiology
Normal functions malfunctioning
Muscular System
Movement
Respiratory
Voice box, breathing
Functional Classifications of neurons
Sensory
Neurons that transmit impulses from sensory receptors in the skin or organs TOWARD the central Nervous System
Interneurons
Neurons that conduct impulses WITHIN the CNS and integrate incoming sensory input to predict the proper motor output
Motor
Neurons that carry impulses away from the CNS to effectors, such as muscular, organs or glands
Excitation-Contraction Coupling
Action potential travels across the entire Sarcolemma and is rapidly conducted into the interior of the muscle fiber by t-tubules
t-tubules make contact with the sarcoplasmic reticulum
releases the calcium from the SR
this triggers a contraction of the skeletal muscle fiber
The Process of Summation
when a neuron uses more than one message to determine if it should depolarize
No Summation
a slowly firing presynaptic neuron causes EPSPs that are far apart in time
Temporal Summation
a rapidly firing presynaptic neuron causes EPSPs that are close in time
Spatial Summation
if more than one presynaptic neuron fires at the same time, EPSPs are generated at different locations on the neuron
Excitatory VS Inhibitory
Excitatory
open channels that depolarize the membrane
Inhibitory
open channels that hyperpolarize the membrane
Clostridium Tetani
Blocks the release of inhibitory neurotransmitters at the neuromuscular junction, causing the muscle to continuously contract
Normal cellular process
cause the muscle to contract using neurotransmitters