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Chapter 19 Lecture 6 (Gas Gangrene (Diagnosis, Treatment, & Prevention…
Chapter 19 Lecture 6
Gas Gangrene
When blood supply to tissue is interrupted a wound becomes ischemic. The tissue becomes anaerobic and death (necrosis) sets in.
IF a wound gets infected with endospores of anaerobic Clostridium then gas gangrene develops in the dead tissue
S/S the bacterium makes toxins that kill surrounding tissues, giving the bacterium more nutrients and increasing the size of the anaerobic environment so the rapidly growing bacteria move into the surrounding tissue– which causes more death of tissue
S/S- The immediate result is intense pain at the initial site of infection , followed by gas gangrene (blackening of the skin and muscle and crepitation) Crepitation comes from the hydrogen and carbon dioxide gases which can give off a frothy brownish fluid.
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Diagnosis, Treatment, & Prevention
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Medical emergency, doc must intervene quickly and aggressively to stop the spread of necrosis
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Cutaneous Anthrax
A bacterial disease that affects the skin! It has three distinct clinical manifestations (can show up three different ways) gastrointestinal, inhalation and cutaneous.
Gastrointestinal is rare, inhalation will be discussed at a later time
Cutaneous begins when Bacillus anthracis endospores (shed by infected animal) enter a wound in your skin.
Localized itching followed by a raised lesion that eventually will form a painless black eschar within 7-10 days
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Diseases of Poxviruses
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S/S
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Begin as flat, reddened macules
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Those infected will also develop a fever as high as 107 degrees F, malaise, delirium and prostration
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