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(Sentinel cells (NOD (inflammasome, sterile inflammation primarily…
Sentinel cells
NOD
inflammasome
sterile inflammation primarily (DAMPS)
TLR
NFkeppaB
cytokines
inflammation
non-sterile
sterile (DAMPS)
leukocyte reqruiment
phagocytosis, OB, NETs
addaptive
dendritic cells (APCs)
Migration due to chemokines
activation T-cells and B-cells.
T-cell
clonal expansion
IL-2
CD8
Kill pathogens using perforin and granzymes
CD4
cyotkine production
subset:
Th1
IL-2
1 more item...
Th2
IL-4
1 more item...
Th17
IL-6, TGF-beta
1 more item...
Tregs
TGF-beta
1 more item...
B cell
T cell dependent
T-B
Cd40 and CD40L
compement factor (c3d-CR2)
plasma cells
isotype switching
affinity maturation
antibody production
T independent
polysacharides.
Nk cells and IgG.