A small set of organic molecules produced by basophils, which release through circulation, and mast cells, found in connective tissue which release if stimulated by an infection. It heavily affects the body's immune response as it raises the capillaries' permeability to white blood cells and some proteins, permitting early pathogen engagement at the site of infection. They may cause inflammation/hives, itching, sneezing, watery eyes, or more. Categorized as an allergy and antihistamines work to as a drug to oppose the activity of histamine receptors.