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Sub-Topic 1
Risk Assessment Risk-assessment-graphic-1 - Coggle Diagram
Sub-Topic 1
Risk Assessment
A. What is Risk Assessment?
WHO. (n.d.). WHO Risk assessment.
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- A powerful tool for evaluating strategies to reduce diseases & for future research needs
- Scientist, risk manager & policy makers work together proactive and responsive - develop food safety system to address threats in food supply chain
Four Steps in Risk Assessment
WHO, 2021
1. Hazard identification
- Identification of known or potential health effects associated with a particular agent
- What agent present in food and cause adverse health effect?
2. Hazard characterization
- Evaluation of the nature of the adverse effects associated with biological, chemical, and physical agents which may be present in food
- Dose-response assessment (what is the nature of the effect and at what dose)
3. Exposure assessment
- Evaluation of the degree of intake likely to occur
- What is the likely frequency & level of exposure to the agent at the time consumption
4. Risk characterization
- Output of the process (including all uncertainty & variability)
- Integration of hazard identification, hazard characterization and exposure assessment into an estimation of the adverse effects likely to occur in a given population, including attendant uncertainties
B. Principles in Risk
Assessment
- Functional separation - scientific integrity between risk assessor & manager
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- Follow structure approach
- Continuous process - periodical evaluation & monitoring
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- Primarily concern - Human Health
- Clear, interactive with ALL interested parties
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Cost Risk Assessment
Cost of Reformulating Foods and Cosmetics
help estimate the costs incurred in reformulation due to changes in regulations
provides information on the process of reformulation and a description of the underlying assumptions and calculations used in developing the model
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Chemical Risk Assessment
SHEDS models
- this model are probabilistic models that estimate human chemical exposures from inhalation, skin contact, and dietary and non-dietary ingestion.
Cumulative and Aggregate Risk Evaluation System Next Generation (CARES NG)
- used to estimate aggregate (single chemical) and cumulative (multiple chemicals) exposure to pesticides from multiple routes and sources
- pesticide residues in food or drinking water
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