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Unit 3 Integumentary system (functions (sense environment (pain, touch,…
Unit 3 Integumentary system
Skin
Epidermis
Keratinized stratified squamous epithelium
structure
Stratum basale (on basement membrane)
stem cells
Merkel cells
sensory but no axon
Langerhans cells
immunity
release antigen
Melanocytes
Basement membrane (dermis)
Stratum spinosum
keratinocytes
have desmosomes
langerhans cells
cellular projections of melanocytes
flexibility
Stratum granulosum (keratinocytes)
keratohyalin granules
lamellar granules (lipids)
function
barrier from microoganism
prevent water loss
Stratum lucidum
only in thick skin
feet
palm
Stratum corneum
keratinocytes
dead filled with keratin
Innervated & Avascularized
Cells
Keratinocytes 90%
Melanocytes 8%
location
Stratum basale
function
color
UV protection
produce
melanin
Langerhans cells
immune cells
antigen presenting cells
derive from bone marrow
Merkel cells
Mechanoreceptors
location
Stratum basale
Dermis
merkel disc
Papillary region
areolar connective tissue
dermal papilla
folds increase contact
epidermal bridge
connective tissue
Reticular region
dense irregular connective tissue
glands
sebaceous
sweat
hair follicle
stemm cells
epithelium
connective tissue
structure
dermal root sheath
internal root sheath (epithelial cells)
external root sheath (epidermis)
medulla
eumelanin
phenomelanin
pacinian corpuscles
pressure
fibroblasts
collagen fibers
resistance
elastic fibers
Ruffini corpuscle
pressure
Innervated & Vascularized
sensations
Mechanoreceptors
Merkel cells
Thermoreceptors
Nociceptors
pain
Proprioceptors
position
pH = 5.5
Hair
Glands
Sebaceous
Sweat
Nails
functions
production of vitamin D
thermoregulation
removal of waste (sweat)
sense environment
pain
touch
pressure
1st line of defense
pigmentation
Melanin
Hypodermis not part of skin
adipose
storage
areolar connective tissue
vascularized
storage
Heat (maintain temperature)