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Intracranial Pressure (Influences (Changes in temperature, Intra-abdominal…
Intracranial Pressure
Influences
Changes in temperature
Intra-abdominal and/or Intra-thoracic pressure changes
Changes in blood gassess
Arterial and/or Venous pressure changes
Changes in posture
Cerebral Blood Flow
Amount of blood(mLs) passing through 100 g of brain tissue/min
Autoregulation
Adjusts diameter of blood vessels
Ensures consistent CBF
Only effective if MAP 70-150 mm Hg
Pressure Changes
Compliance is expandability of brain
Impacts effect of volume change of pressure
Compliance=Volume/Pressure
Stages of Increased ICP
Stage 1: Total Compensation
Stage 2: Decreased compensation
Stage 3: Failing Compensation
Stage 4: Herniation Imminent to Death
Regulation
Monro-Kellie doctrine
Normal adaptations
Changes in tissue brain volume
Changes in intracranial blood volume
Changes in CSF volume
Normal ICP: 5-15 mm Hg
Cerebral Edema
Increased extravascular fluid in brain
Variety of causes
Three types: Vasogenic, Cytotoxic, Interstitial